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Chemical Structure : LB42908
Catalog No.: PC-63362Not For Human Use, Lab Use Only.
LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras..
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LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras.
| M.Wt | 533.62 | |
| Formula | C32H31N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lee H, et al. Bioorg Med Chem Lett. 2001 Dec 3;11(23):3069-72.
2. Kim HJ, et al. Bioorg Med Chem Lett. 2012 May 1;22(9):3067-71.
3. Kim HS, et la. Toxicol Appl Pharmacol. 2006 Sep 15;215(3):317-29.
4. Lee SK, et al. Int J Cancer. 2006 May 1;118(9):2172-81.
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