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LDC3140

Chemical Structure : LDC3140

CAS No.: 1453833-30-1

LDC3140 (LDC 3140)

Catalog No.: PC-21922Not For Human Use, Lab Use Only.

LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9.

Physicochemical Properties

M.Wt 423.57
Formula C23H33N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(dimethylamino)benzyl)-8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine

References

1. Kelso TW, et al. Mol Cell Biol. 2014 Oct 1;34(19):3675-88.

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