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Chemical Structure : LDN-75654
Catalog No.: PC-61636Not For Human Use, Lab Use Only.
LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM.
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LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice.
| M.Wt | 282.699 | |
| Formula | C13H12ClFN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610.
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