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Chemical Structure : LDN-76070
Catalog No.: PC-61635Not For Human Use, Lab Use Only.
LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM.
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LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).
| M.Wt | 410.239 | |
| Formula | C18H17BrFNO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610.
2. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18.
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