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Chemical Structure : LLL3
Catalog No.: PC-61660Not For Human Use, Lab Use Only.
LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities.
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LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities.
LLL3 also inhibits viability of U87, U373, and U251 glioblastoma cells as well as induces apoptosis of these glioblastoma cell lines.
LLL3 exhibits prolonged survival in U87 glioblastoma tumour-bearing mice.
| M.Wt | 266.252 | |
| Formula | C16H10O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fuh B, et al. Br J Cancer. 2009 Jan 13;100(1):106-12.
2. Fossey SL, et al. BMC Cancer. 2009 Mar 10;9:81.
3. Mencalha AL, et al. Cancer Chemother Pharmacol. 2010 May;65(6):1039-46.
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