Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : LMD-A
Catalog No.: PC-60855Not For Human Use, Lab Use Only.
LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM; inhibits 10 nM CCL1-induced activation of CCR8 with EC50 of 12 nM, inhibits 4DE4 cells cell migration induced by 3 nM CCL1 with EC50 of 0.58 nM.
| M.Wt | 508.637 | |
| Formula | C27H32N4O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Rummel PC, et al. Br J Pharmacol. 2012 Nov;167(6):1206-17.
2. Barington L, et al. J Biol Chem. 2016 Jul 29;291(31):16208-20.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
