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Chemical Structure : LSD1 inhibitor 24
Catalog No.: PC-35794Not For Human Use, Lab Use Only.
LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM.
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LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM.
LSD1 inhibitor 24 demonstrates attenuating the hERG inhibition and improving oral bioavailability.
| M.Wt | 505.982 | |
| Formula | C26H25ClFN7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nie Z, et al. Bioorg Med Chem Lett. 2018 Nov 3. pii: S0960-894X(18)30855-2.
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