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Chemical Structure : LUF6000
CAS No.: 890087-21-5
Catalog No.: PC-43415Not For Human Use, Lab Use Only.
LUF6000 is a potent, selective, positive allosteric modulator (enhancer) of human A3 adenosine receptor, enhance Emax but without affecting agonist potency.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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LUF6000 is a potent, selective, positive allosteric modulator (enhancer) of human A3 adenosine receptor, enhance Emax but without affecting agonist potency.
LUF6000 enhance sagonist efficacy in a functional assay by 45% and decreases dissociation rate similarly without influencing agonist potency.
LUF6000 is superior to that of DU124183.
| M.Wt | 411.327 | |
| Formula | C22H20Cl2N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3H-Imidazo[4,5-c]quinolin-4-amine, 2-cyclohexyl-N-(3,4-dichlorophenyl)- |
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1. Göblyös A, et al. J Med Chem. 2006 Jun 1;49(11):3354-61.
2. Gao ZG, et al. BMC Pharmacol. 2008 Dec 12;8:20.
3. Gao ZG, et al. Biochem Pharmacol. 2011 Sep 15;82(6):658-68.
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