LY311727 | PLA2 inhibitor | Probechem Biochemicals

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Chemical Structure : LY311727

CAS No.: 164083-84-5

LY311727 (LY-311727)

Catalog No.: PC-26699Not For Human Use, Lab Use Only.

LY311727 (LY-311727) is a potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 (group IIA sPLA2, PLA2-IIA, hnps-PLA2) with IC50 of 0.19 nM, 1,500-fold selectivity against porcine pancreatic s-PLA2.

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5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$198	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	430.44
Formula	C22H27N2O5P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3-((3-(2-Amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl)oxy)propyl)phosphonic acid

References

1. Schevitz RW, et al. Nat Struct Biol. 1995 Jun;2(6):458-65.

2. Fleisch JH, et al. J Pharmacol Exp Ther. 1996 Jul;278(1):252-7.

3. Fox N, et al. Eur J Pharmacol. 1996 Jul 18;308(2):195-203.

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LY311727 (LY-311727)

Biological Activity

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References

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