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Chemical Structure : Larixyl acetate
CAS No.: 4608-49-5
Catalog No.: PC-60610Not For Human Use, Lab Use Only.
Larixyl acetate is a potent, selective TRPC6 channel inhibitor with IC50 of 0.1-0.6 uM, 12- and 5-fold selectivity over related TRPC3 and TRPC7.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Larixyl acetate is a potent, selective TRPC6 channel inhibitor with IC50 of 0.1-0.6 uM, 12- and 5-fold selectivity over related TRPC3 and TRPC7.
Larixyl acetate inhibits native TRPC6-like [Ca(2+)]i signals in diacylglycerol-stimulated rat pulmonary artery smooth muscle cells.
Larixyl acetate prevents acute hypoxia-induced vasoconstriction in isolated mouse lungs.
| M.Wt | 348.527 | |
| Formula | C22H36O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1S,4S,4aR,8aS)-4-((S)-3-hydroxy-3-methylpent-4-en-1-yl)-4a,8,8-trimethyl-3-methylenedecahydronaphthalen-1-yl acetate |
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1. Urban N, et al. Mol Pharmacol. 2016 Jan;89(1):197-213.
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