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LasR-IN-6

Chemical Structure : LasR-IN-6

CAS No.: 872546-39-9

LasR-IN-6

Catalog No.: PC-28636Not For Human Use, Lab Use Only.

LasR-IN-6 (Cpmpound 7d) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 0.261 uM, has MIC of 62.5 uM against P. aeruginosa PAO1, significantly suppressed key virulence factors, including protease production, biofilm formation, and motility phenotypes in P. aeruginosa.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LasR-IN-6 (Cpmpound 7d) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 0.261 uM, has MIC of 62.5 uM against P. aeruginosa PAO1, significantly suppressed key virulence factors, including protease production, biofilm formation, and motility phenotypes in P. aeruginosa.

Physicochemical Properties

M.Wt 469.46
Formula C25H19N5O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-(2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl)-2-methoxyphenoxy)-N-(4-nitrophenyl)acetamide

References

1. Mohammed EZ, et al. Bioorg Chem. 2026 Sep 15;180:110160.

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