LasR inhibitor 2g

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Chemical Structure : LasR inhibitor 2g

Catalog No.: PC-28637Not For Human Use, Lab Use Only.

LasR inhibitor 2g is a potent, small molecule inhibitor of P. aeruginosa QS hierarchy LasR, demonstrated exceptional biofilm inhibition with IC50 of 0.14 uM, binds LasR with high affinity (KD=38.97 uM), suppresses LasR-regulated virulence pathways, reduces pyocyanin production and bacterial motility, shows synergistic antibiotic enhancement activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	324.26
Formula	C15H11F3N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-nitrophenyl)-N-(3-(trifluoromethyl)phenyl)acetamide

References

1. Huang Y, et al. Acta Pharm Sin B. 2026 Oct;16(10):6852-6874.

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