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Chemical Structure : Linagliptin
CAS No.: 668270-12-0
Catalog No.: PC-42508Not For Human Use, Lab Use Only.
Linagliptin (BI-1356) is a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor with IC50 of 1 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $88 | In stock | |
| 100 mg | $158 | In stock | |
| 200 mg | $248 | In stock | |
| 1 g | Get quote |
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Linagliptin (BI-1356) is a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor with IC50 of 1 nM.
Linagliptin (BI-1356) shows no significant inhibition on hERG and muscarinic receptor M1 at 1 uM.
Linagliptin (BI-1356) shows considerable blood glucose lowering in different animal species.
| M.Wt | 472.5422 | |
| Formula | C25H28N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- |
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1. Eckhardt M, et al. J Med Chem. 2007 Dec 27;50(26):6450-3.
2. Thomas L, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82.
3. Thomas L, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):556-63.
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