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Lusutrombopag

Chemical Structure : Lusutrombopag

CAS No.: 1110766-97-6

Lusutrombopag (S-888711)

Catalog No.: PC-45744Not For Human Use, Lab Use Only.

An orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist.

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5 mg $168 In stock
10 mg $280 In stock
25 mg $600 In stock
50 mg $880 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist; acts selectively on the human thrombopoietin receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels;

Other Indication

Approved

Physicochemical Properties

M.Wt 591.5458
Formula C29H32Cl2N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-

References

1. Kim ES. Drugs. 2016 Jan;76(1):155-8.

2. Sakamaki A, et al. Clin J Gastroenterol. 2017 Jun;10(3):261-264.

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