Lys01 | Autophagy inhibitor | Probechem Biochemicals

Chemical Structure : Lys01

CAS No.: 1391426-22-4

Lys01 (Lys 01, Lys-01)

Catalog No.: PC-60600Not For Human Use, Lab Use Only.

Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 uM respectively.

Packing	Price	Stock
5 mg	$198	In stock
10 mg	$328	In stock
25 mg	$528	In stock
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Biological Activity

Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 uM respectively.

Physicochemical Properties

M.Wt	440.372
Formula	C23H23Cl2N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine

References

1. McAfee Q, et al. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8253-8.

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Lys01 (Lys 01, Lys-01)

Biological Activity

Physicochemical Properties

References

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