Lyz-866

Chemical Structure : Lyz-866

Catalog No.: PC-25771Not For Human Use, Lab Use Only.

Lyz-866 is a potent, selective Gi-biased agonist of cholecystokinin (CCK) B receptor (CCKBR) with EC50 of 0.27 nM.

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Biological Activity

Lyz-866 is a potent, selective Gi-biased agonist of cholecystokinin (CCK) B receptor (CCKBR) with EC50 of 0.27 nM.

M.Wt	717.64
Formula	C31H37BrN6O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-((S)-2-((S)-2-acetamido-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-(((S)-1-amino-3-(3-bromophenyl)-1-oxopropan-2-yl)amino)-4-oxobutanoic acid

1. Wang JL, et al. Cell. 2025 Nov 20:S0092-8674(25)01238-3.