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Chemical Structure : M5717
CAS No.: 1469439-69-7
Catalog No.: PC-72956Not For Human Use, Lab Use Only.
M5717 (DDD107498, M 5717, Cabamiquine) is a potent, specific P. falciparum translation elongation factor 2 inhibitor (PfeEF2).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $328 | In stock | |
| 25 mg | $528 | In stock | |
| 100 mg | $1380 | In stock | |
| 1 g | Get quote |
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M5717 (DDD107498, M 5717, Cabamiquine) is a potent, specific P. falciparum translation elongation factor 2 inhibitor (PfeEF2).
M5717 demonstrated through high potency against asexual blood-stage P. falciparum parasites as well as in vivo by means of the well-established P. falciparum SCID mouse model.
| M.Wt | 462.569 | |
| Formula | C27H31FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
6-fluoro-2-(4-(morpholinomethyl)phenyl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoline-4-carboxamide |
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1. Arez F, et al. ACS Infect Dis. 2019 Nov 8;5(11):1831-1842.
2. Rottmann M, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02181-19.
3. McCarthy JS, et al. Lancet Infect Dis. 2021 Dec;21(12):1713-1724.
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