MALT1 inhibitor 8

Chemical Structure : MALT1 inhibitor 8

Catalog No.: PC-49479Not For Human Use, Lab Use Only.

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

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Biological Activity

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

Physicochemical Properties

M.Wt	412.805
Formula	C16H16ClF3N8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1s,4s)-N1-(3-chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N4-(2-(trifluoromethyl)pyrimidin-4-yl)cyclohexane-1,4-diamine

References

1. Stefan Schiesser, et al. Eur J Med Chem. 2022 Jan 5;227:113925.

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