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Chemical Structure : MAP4K4-IN-11e
Catalog No.: PC-61165Not For Human Use, Lab Use Only.
MAP4K4-IN-11e is a potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases.
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MAP4K4-IN-11e is a potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases.
MAP4K4 is active at much lower concentration in the cellular neurite outgrowth assay and may exhibit better pharmacokinetic properties.
| M.Wt | 301.342 | |
| Formula | C17H19NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Schröder P, et al. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403.
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