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Chemical Structure : MAX-40279
CAS No.: 2070931-57-4
Catalog No.: PC-72411Not For Human Use, Lab Use Only.
MAX-40279 (MAX40279, EX-A4057) is a dual inhibitor of FLT3 and FGFR for the treatment of Acute Myeloid Leukemia (AML).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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MAX-40279 (MAX40279, EX-A4057) is a dual inhibitor of FLT3 and FGFR for the treatment of Acute Myeloid Leukemia (AML).
MAX-40279 demonstrated potent inhibition of both FLT3 and FGFR with excellent drug concentration in the bone marrow.
MAX-40279 is designed to overcome the observed drug resistance of the current FLT3 inhibitors due to the bone marrow FGF/FGFR pathway activation.
| M.Wt | 438.525 | |
| Formula | C22H23FN6OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- |
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1. Patent WO2021180032A1.
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