MAX10181 (MAX-10181)

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Chemical Structure : MAX10181

CAS No.: 2171558-14-6

Catalog No.: PC-20279Not For Human Use, Lab Use Only.

MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.

Packing	Price	Stock
5 mg	$248	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.

Physicochemical Properties

M.Wt	527.54
Formula	C29H28F3NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-((3-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylstyryl)-4-(trifluoromethyl)benzyl)amino)-3-hydroxy-2-methylpropanoic acid

References

1. Yuguang Wang, et al. Cancer Res (2019) 79 (13_Supplement): LB-018.

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