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MC4-NN2-0453

Chemical Structure : MC4-NN2-0453

CAS No.: 1228015-10-8

MC4-NN2-0453

Catalog No.: PC-26944Not For Human Use, Lab Use Only.

MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.

Physicochemical Properties

M.Wt 2092.36
Formula C96H146N28O25
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Lysinamide, N-[2-[2-[2-[[1-oxo-16-(2H-tetrazol-5-yl)hexadecyl]amino]ethoxy]ethoxy]acetyl]glycyl-L-seryl-L-glutaminyl-L-histidyl-3-[[2-[bis(carboxymethyl)amino]acetyl]amino]-L-alanyl-L-norleucyl-L-α-glutamyl-(4R)-4-hydroxy-L-prolyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, (7→12)-lactam

References

1. Kilian Conde-Frieboes, et al. J Med Chem. 2012 Mar 8;55(5):1969-77.

2. Jane E Royalty, et al. J Clin Pharmacol. 2014 Apr;54(4):394-404.

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