Chemical Structure : MC4-NN2-0453
CAS No.: 1228015-10-8
Catalog No.: PC-26944Not For Human Use, Lab Use Only.
MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.
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MC4-NN2-0453 is a potent, long-acting, selective, peptide melanocortin-4 receptor (MC4R) agonist, >1000-fold selective over MC1R.
| M.Wt | 2092.36 | |
| Formula | C96H146N28O25 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
L-Lysinamide, N-[2-[2-[2-[[1-oxo-16-(2H-tetrazol-5-yl)hexadecyl]amino]ethoxy]ethoxy]acetyl]glycyl-L-seryl-L-glutaminyl-L-histidyl-3-[[2-[bis(carboxymethyl)amino]acetyl]amino]-L-alanyl-L-norleucyl-L-α-glutamyl-(4R)-4-hydroxy-L-prolyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, (7→12)-lactam |
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1. Kilian Conde-Frieboes, et al. J Med Chem. 2012 Mar 8;55(5):1969-77.
2. Jane E Royalty, et al. J Clin Pharmacol. 2014 Apr;54(4):394-404.

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