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MDOLL-0591

Chemical Structure : MDOLL-0591

CAS No.:

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MDOLL-0591 (MDOLL0591)

Catalog No.: PC-27445Not For Human Use, Lab Use Only.

MDOLL-0591 is a selective inhibitor targeting chikungunya virus (CHIKV) nsP3 macrodomain with IC50 of 10 uM, shows antiviral activity against CHIKV in cell culture.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MDOLL-0591 is a selective inhibitor targeting chikungunya virus (CHIKV) nsP3 macrodomain with IC50 of 10 uM, shows antiviral activity against CHIKV in cell culture.

Physicochemical Properties

M.Wt 379.43
Formula C20H17N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((4,6-dihydroxypyrimidin-2-yl)thio)-1-(1,2-dimethyl-3H-benzo[e]indol-3-yl)ethan-1-one

References

1. Duong MTH, et al. Eur J Med Chem. 2026 Jul 22;318:119182.

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