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MF266-3

Chemical Structure : MF266-3

CAS No.: 244101-03-9

MF266-3 (MF 266-3)

Catalog No.: PC-63011Not For Human Use, Lab Use Only.

MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM; displayes a relatively good selectivity over other prostanoid receptors.

Physicochemical Properties

M.Wt 570.882
Formula C27H21BrClNO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthylmethyl)phenyl]acrylamide

References

1. Clark P. et al. J Pharmacol Exp Ther. 2008 May;325(2):425-34.

2. Juteau H, et al. Bioorg Med Chem. 2001 Aug;9(8):1977-84.

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