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MGCD-265 analog

Chemical Structure : MGCD-265 analog

CAS No.: 875337-44-3

MGCD-265 analog (MGCD 265 analog;MGCD265 analog)

Catalog No.: PC-42768Not For Human Use, Lab Use Only.

An analog of MGCD-265, and an orally bioavailable multikinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An analog of MGCD-265, and an orally bioavailable multikinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.

Physicochemical Properties

M.Wt 517.5977
Formula C26H20FN5O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneacetamide, N-[[[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-

References

1. Claridge S, et al. 2008 May 1;18(9):2793-8.

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