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Chemical Structure : MIV 150
Catalog No.: PC-61409Not For Human Use, Lab Use Only.
MIV 150 (PC-815) is a high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM.
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MIV 150 (PC-815) is a high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM.
MIV 150 possesses poor oral bioavailability, and demonstrates efficacy when formulated as a topical microbicide (PC-815: Carrageenan gel formulation).
| M.Wt | 368.4 | |
| Formula | C19H17FN4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Geitmann M, et al. J Med Chem. 2006 Apr 20;49(8):2367-74.
2. Fernández-Romero JA, et al. Sex Transm Dis. 2007 Jan;34(1):9-14.
3. Singer R, et al. Sci Transl Med. 2012 Sep 5;4(150):150ra123.
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