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MJM-1

Chemical Structure : MJM-1

CAS No.:

MJM-1

Catalog No.: PC-72875Not For Human Use, Lab Use Only.

MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line.
MJM-1 injected intraperitoneally (i.p.) crossed the BBB in mice and could be detected in the hippocampus, a brain region that mediates memory.
MJM-1 (post-training i.p. administration) enhanced hippocampus-dependent spatial memory consolidation in male mice.

Physicochemical Properties

M.Wt 462.66
Formula C22H38O6S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Jawad B Belayet, et al. J Med Chem. 2022 Feb 24;65(4):3388-3403.

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