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Chemical Structure : MK-571 sodium salt
CAS No.: 115103-85-0
Catalog No.: PC-45775Not For Human Use, Lab Use Only.
MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | $458 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM.
MK-571 sodium effectively blocks LTD4 activation of recombinant human and mouse CysLT1 receptors.
MK-571 sodium also is an inhibitor of multidrug resistance protein-1 (MRP1) mediated transportorally active.
| M.Wt | 537.069 | |
| Formula | C26H26ClN2NaO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 50 mM in H2O (26.85 mg/mL, ultrasonic needed) |
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| Chemical Name/SMILES |
Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-, sodium salt, (E)- (9CI) |
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1. Gauthier JY, et al. J Med Chem. 1990 Oct;33(10):2841-5.
2. Vellenga E, et al. Br J Pharmacol. 1999 May;127(2):441-8.
3. Lynch K, et al. Nature. 1999 Jun 24;399(6738):789-93.
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