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Chemical Structure : ML191
CAS No.: 931695-79-3
Catalog No.: PC-35027Not For Human Use, Lab Use Only.
ML191 (CCG-152883) is a potent, selective GPR55 antagonist with 160 nM potency for GPR55 and >100-fold selectivity against GPR35, CB1 and CB2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | $588 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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ML191 (CCG-152883) is a potent, selective GPR55 antagonist with 160 nM potency for GPR55 and >100-fold selectivity against GPR35, CB1 and CB2.
ML191 (CCG-152883) inhibits LPI- mediated ERK1/2 phosphorylation with IC50 of 0.4 uM.
ML191 (CCG-152883) inhibits trafficking induced by 10 μM LPI in the β-arrestin trafficking assay with IC50 of 1.08 uM.
| M.Wt | 403.482 | |
| Formula | C24H25N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-phenyl-3-(1-(1-(p-tolyl)cyclopropane-1-carbonyl)piperidin-4-yl)-1,3,4-oxadiazol-2(3H)-one |
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1. Heynen-Genel S, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Kotsikorou E, et al. Biochemistry. 2013 Dec 31;52(52):9456-69.
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