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ML251

Chemical Structure : ML251

CAS No.: 1486482-16-9

ML251 (ML 251)

Catalog No.: PC-38084Not For Human Use, Lab Use Only.

ML251 is a potent, selective inhibitor of T. brucei phosphofructokinase (PFK) with IC50 of 15 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML251 is a potent, selective inhibitor of T. brucei phosphofructokinase (PFK) with IC50 of 15 nM.
ML251 demonstrated micromolar activity in cultured parasite growth assays.

Physicochemical Properties

M.Wt 426.27
Formula C17H13Cl2N3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-dichlorophenyl)-N-(4-(N-(isoxazol-3-yl)sulfamoyl)phenyl)acetamide

References

1. Brimacombe KR, et al. ACS Med Chem Lett. 2013 Oct 30;5(1):12-7.

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