Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ML276
Catalog No.: PC-20587Not For Human Use, Lab Use Only.
ML276 (ML 276) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 889 nM, with no activity against human G6PD.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ML276 (ML 276) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 889 nM, with no activity against human G6PD.
ML276 inhibits P. falciparum growth in vitro with IC50 values of 2.3 uM for the chloroquine sensitive 3D7 strain and 3.7 uM for the chloroquine resistant Dd2 strain.
ML276 inhibits PfGluPho activity by competing with the substrate.
| M.Wt | 425.52 | |
| Formula | C23H24FN3O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Preuss J, et al. J Med Chem. 2012 Aug 23;55(16):7262-72.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
