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Chemical Structure : ML282
CAS No.: 314042-01-8
Catalog No.: PC-62365Not For Human Use, Lab Use Only.
ML282 (CID 1067700) is a competitive small molecule inhibitor of nucleotide binding by Ras-related GTPases, binds the nucleotide binding pocket of Rab7 with Ki value of 13 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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ML282 (CID 1067700) is a competitive small molecule inhibitor of nucleotide binding by Ras-related GTPases, binds the nucleotide binding pocket of Rab7 with Ki value of 13 nM.
ML282 prevents BODIPY-linked GTP and GDP binding with EC50 values of 11.2 and 21 nM, respectively.
ML282 suppresses T cell-dependent and T cell-independent Ab responses.
| M.Wt | 390.472 | |
| Formula | C18H18N2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid |
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1. Agola JO, et al. ACS Chem Biol. 2012 Jun 15;7(6):1095-108.
2. Lam T, et al. J Immunol. 2016 Nov 15;197(10):3792-3805.
3. Agola JO, et al. Methods Mol Biol. 2015;1298:331-54.
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