ML293

Chemical Structure : ML293

Catalog No.: PC-24345Not For Human Use, Lab Use Only.

ML293 is a selective, brain penetrant M4 mAChR positive allosteric modulator (PAM) with EC50 of 1.3M (hM4), selective against the four other muscarinic subtypes.

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Biological Activity

ML293 is a selective, brain penetrant M4 mAChR positive allosteric modulator (PAM) with EC50 of 1.3M (hM4), selective against the four other muscarinic subtypes.

Physicochemical Properties

M.Wt	299.35
Formula	C15H13N3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicotinamide

References

1. Salovich JM, et al. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5084-8.

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ML293

Biological Activity

Physicochemical Properties

References

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