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ML339

Chemical Structure : ML339

CAS No.: 2080300-49-6

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ML339 (ML 339)

Catalog No.: PC-38130Not For Human Use, Lab Use Only.

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM)。
    ML 339 exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors.

    Physicochemical Properties

    M.Wt 502.008
    Formula C26H32ClN3O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 1 Month
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-

    References

    1. Satyamaheshwar Peddibhotla, et al. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126899.

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