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Chemical Structure : ML368
Catalog No.: PC-62112Not For Human Use, Lab Use Only.
ML368 (SR 9186) is a potent, selective cytochrome P450 enzyme CYP3A4 inhibitor with IC50 of 4 nM (convert testosterone to hydroxytestosterone), displays >2,000-fold selectivity over CYP3A5..
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ML368 (SR 9186) is a potent, selective cytochrome P450 enzyme CYP3A4 inhibitor with IC50 of 4 nM (convert testosterone to hydroxytestosterone), displays >2,000-fold selectivity over CYP3A5.
| M.Wt | 430.5 | |
| Formula | C26H18N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li X, et al. Drug Metab Dispos. 2012 Sep;40(9):1803-9.
2. Towles JK, et al. Drug Metab Dispos. 2016 Oct;44(10):1584-97.
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