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Chemical Structure : ML 604440
CAS No.: 1140517-08-3
Catalog No.: PC-60968Not For Human Use, Lab Use Only.
ML 604440 (ML604440, ML-604440) is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 100 mg | Get quote |
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ML 604440 (ML604440, ML-604440) is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor.
ML 604440 reduces the cleavage of Ac-PAL-AMC by proteasomes from WT mice in a dose-dependent manner (12.5-200 nM), with no affect on β5/LMP7.
| M.Wt | 388.194 | |
| Formula | C17H24BF3N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-(3-methyl-1-(2-methyl-2-(2-(trifluoromethyl)benzamido)propanamido)butyl)boronic acid |
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1. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
2. Basler M, et al. J Immunol. 2012 Aug 15;189(4):1868-77.
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