MLEB-1934 | Bacterial DNA gyrase inhibitor

Chemical Structure : MLEB-1934

Catalog No.: PC-22162Not For Human Use, Lab Use Only.

MLEB-1934 is a potent bacterial DNA gyrase inhibitor with MIC of 0.25 μg/mL in MRSA, targets the allosteric pocket of the gyrase.

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Biological Activity

MLEB-1934 is a potent bacterial DNA gyrase inhibitor with MIC of 0.25 μg/mL in MRSA, targets the allosteric pocket of the gyrase.

M.Wt	467.54
Formula	C27H28F3N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(((6aR,9S,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl)-3-(4-(trifluoromethyl)phenyl)acrylamide

1. Shawn French, et al. Cell Rep. 2024 Apr 4;43(4):114053.