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Chemical Structure : MM-206
Catalog No.: PC-61161Not For Human Use, Lab Use Only.
MM-206 is a novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD).
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MM-206 is a novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD).
MM-206 also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM,
| M.Wt | 497.454 | |
| Formula | C22H12F5NO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Minus MB, et al. Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13085-9.
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