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MMAF-OMe

Chemical Structure : MMAF-OMe

CAS No.: 863971-12-4

MMAF-OMe (Monomethyl auristatin F methyl ester)

Catalog No.: PC-46001Not For Human Use, Lab Use Only.

An antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells; an ADC payload.

Physicochemical Properties

M.Wt 745.9887
Formula C40H67N5O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO

Chemical Name/SMILES

L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, methyl ester

References

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