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MMPI-1154

Chemical Structure : MMPI-1154

CAS No.: 1382722-47-5

MMPI-1154 (MMPI1154)

Catalog No.: PC-63509Not For Human Use, Lab Use Only.

MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.
    MMPI-1154 shows significant cardio-cytoprotecion, significantly decreases infarct size when applied at 1 μM in an ex vivo model for acute myocardial infarction.

    Physicochemical Properties

    M.Wt 445.494
    Formula C26H24FN3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(((4-(benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-4-carboxylic acid

    References

    1. Bencsik P, et al. Front Pharmacol. 2018 Apr 5;9:296.

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