MMV020291 (MMV291)

Chemical Structure : MMV020291

Catalog No.: PC-27971Not For Human Use, Lab Use Only.

MMV020291 (MMV291) is a specific antimalarial inhibitor of red blood cells (RBC) invasion, specifically blocks merozoite entry into RBCs, reduces actin polymerisation that is required by the merozoite stage parasites to invade RBCs.

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Biological Activity

MMV020291 (MMV291) is a specific antimalarial inhibitor of red blood cells (RBC) invasion, specifically blocks merozoite entry into RBCs, reduces actin polymerisation that is required by the merozoite stage parasites to invade RBCs.

Physicochemical Properties

M.Wt	407.57
Formula	C21H33N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-((4-(tert-butyl)phenyl)sulfonyl)piperazin-1-yl)-1-(pyrrolidin-1-yl)propan-1-one

References

1. Dans MG, et al. Int J Parasitol. 2020 Mar;50(3):235-252.

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