MMV022224 | PfPK6 inhibitor | Probechem Biochemicals

Chemical Structure : MMV022224

MMV022224 (TCMDC-132409, MMV-022224, TCMDC132409)

Catalog No.: PC-27181Not For Human Use, Lab Use Only.

MMV022224 (TCMDC-132409) is a potent inhibitor of P. falciparum in vitro with low resistance, targets P. falciparum protein kinase 6 (PfPK6) with IC50 of 0.8 uM.

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Biological Activity

MMV022224 (TCMDC-132409) is a potent inhibitor of P. falciparum in vitro with low resistance, targets P. falciparum protein kinase 6 (PfPK6) with IC50 of 0.8 uM.

Physicochemical Properties

M.Wt	384.53
Formula	C25H28N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,1'-((1H-pyrrolo[2,3-b]pyridine-2,4-diyl)bis(4,1-phenylene))bis(N,N-dimethylmethanamine)

References

1. Aisha J Syed, et al. ACS Infect Dis. 2026 Jun 25. doi: 10.1021/acsinfecdis.6c00276.

2. Sibasish Sarangi, et al. Exp Parasitol. 2025 Jun:273:108947.

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MMV022224 (TCMDC-132409, MMV-022224, TCMDC132409)

Biological Activity

Physicochemical Properties

References

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