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Chemical Structure : MN-64
CAS No.: 92831-11-3
Catalog No.: PC-45620Not For Human Use, Lab Use Only.
MN-64 is a potent and selective inhibitor of Tankyrase 1 (TNKS1) with IC50 of 6 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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MN-64 is a potent and selective inhibitor of Tankyrase 1 (TNKS1) with IC50 of 6 nM.
MN-64 displays 12-fold selectivity over TNKS2 (IC50=72 nM) and no signigicant inhibitory activity on PARP1 and PARP2 (IC50>10 uM).
MN-64 show an Wnt-signaling IC50 of 200 nM in the STF assay.
| M.Wt | 264.3185 | |
| Formula | C18H16O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]- |
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1. Narwal M, et al. J Med Chem. 2013 Oct 24;56(20):7880-9.
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