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Chemical Structure : MPPA
Catalog No.: PC-63331Not For Human Use, Lab Use Only.
MPPA is a potent, orally bioavailable sEH/PDE4 dual inhibitor with IC50 of 2.1 nM and 8.1 nM for hsEH and PDE4, respectively.
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MPPA is a potent, orally bioavailable sEH/PDE4 dual inhibitor with IC50 of 2.1 nM and 8.1 nM for hsEH and PDE4, respectively.
MPPA reduces inflammatory pain in lipopolysaccharide induced inflammatory pain rat model.
| M.Wt | 372.388 | |
| Formula | C18H23F3N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Blöcher R, et al. J Med Chem. 2018 Apr 10. doi: 10.1021/acs.jmedchem.7b01804.
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