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Chemical Structure : MRE-269
CAS No.: 475085-57-5
Catalog No.: PC-46004Not For Human Use, Lab Use Only.
MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.
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|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
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| 100 mg | Get quote |
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MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.
MRE-269 displays no significant affinity for other prostanoid receptors (Ki>2.6 uM).
MRE-269 is the activve metabolite of Selexipag (NS-304).
| M.Wt | 419.5161 | |
| Formula | C25H29N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 51 mg/mL |
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| Chemical Name/SMILES |
Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]- |
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1. Kuwano K, et al. J Pharmacol Exp Ther. 2007 Sep;322(3):1181-8.
2. Kuwano K, et al. J Pharmacol Exp Ther. 2008 Sep;326(3):691-9.
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