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MRGPRX1 agonist 1

Chemical Structure : MRGPRX1 agonist 1

CAS No.: 2377379-39-8

MRGPRX1 agonist 1

Catalog No.: PC-38066Not For Human Use, Lab Use Only.

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.
MRGPRX1 agonist 1 displays favorable distribution to the spinal cord, the presumed site of action for the MRGPRX1-mediated analgesic effects.

Physicochemical Properties

M.Wt 435.498
Formula C23H21N3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(1-aminoisoquinolin-6-yloxy)-4-methylphenyl)-2-methoxybenzenesulfonamide

References

1. Prchalová E, et al. J Med Chem. 2019 Sep 26;62(18):8631-8641.

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