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MRK-898

Chemical Structure : MRK-898

CAS No.: 461450-30-6

MRK-898 (MRK898)

Catalog No.: PC-21943Not For Human Use, Lab Use Only.

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

Physicochemical Properties

M.Wt 400.31
Formula C20H9F5N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[1,1'-Biphenyl]-2-carbonitrile, 2',4-difluoro-5'-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]-

References

1. John R Atack, et al. Curr Top Med Chem. 2011;11(9):1176-202.

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