MRS-2541 | MetRS inhibitor | Probechem Biochemicals

Chemical Structure : MRS-2541

MRS-2541 (MRS2541)

Catalog No.: PC-23309Not For Human Use, Lab Use Only.

MRS-2541 a novel potent inhibitor of methionyl-tRNA synthetase (MetRS) with selective activity against gram-positive bacteria with MIC of 0.063-0.5 ug/mL against Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus species.

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Biological Activity

MRS-2541 a novel potent inhibitor of methionyl-tRNA synthetase (MetRS) with selective activity against gram-positive bacteria with MIC of 0.063-0.5 ug/mL against Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus species.

Physicochemical Properties

M.Wt	473.29
Formula	C21H15Cl2FN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-2-((5-(2-chloro-4,5-dimethoxyphenyl)-6-fluoroimidazo[1,2-a]pyrazin-2-yl)methyl)-1H-imidazo[4,5-b]pyridine

References

1. Molasky NMR, et al. Antimicrob Agents Chemother. 2024 Oct 29:e0074524.

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MRS-2541 (MRS2541)

Biological Activity

Physicochemical Properties

References

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