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MRS-2541

Chemical Structure : MRS-2541

CAS No.: 3064343-50-3

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MRS-2541 (MRS2541)

Catalog No.: PC-23309Not For Human Use, Lab Use Only.

MRS-2541 a novel potent inhibitor of methionyl-tRNA synthetase (MetRS) with selective activity against gram-positive bacteria with MIC of 0.063-0.5 ug/mL against Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus species.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MRS-2541 a novel potent inhibitor of methionyl-tRNA synthetase (MetRS) with selective activity against gram-positive bacteria with MIC of 0.063-0.5 ug/mL against Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus species.

    Physicochemical Properties

    M.Wt 473.29
    Formula C21H15Cl2FN6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-chloro-2-((5-(2-chloro-4,5-dimethoxyphenyl)-6-fluoroimidazo[1,2-a]pyrazin-2-yl)methyl)-1H-imidazo[4,5-b]pyridine

    References

    1. Molasky NMR, et al. Antimicrob Agents Chemother. 2024 Oct 29:e0074524.

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