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MRS2339

Chemical Structure : MRS2339

CAS No.: 436847-13-1

MRS2339 (MRS-2339)

Catalog No.: PC-27706Not For Human Use, Lab Use Only.

MRS2339 is a nucleotide analog agonist of cardiac P2X receptor, improves systolic function in heart failure.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MRS2339 is a nucleotide analog agonist of cardiac P2X receptor, improves systolic function in heart failure.

Physicochemical Properties

M.Wt 391.70
Formula C12H15ClN5O6P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Bicyclo[3.1.0]hexane-2,3-diol, 4-(6-amino-2-chloro-9H-purin-9-yl)-1-[(phosphonooxy)methyl]-, (1R,2R,3S,4R,5S)-

References

1. Kumar TS, et al. J Med Chem. 2010 Mar 25;53(6):2562-76.

2. Zhou SY, et al. J Pharmacol Exp Ther. 2010 Jun;333(3):920-8.

3. Ravi RG, et al. J Med Chem 45: 2090–2100, 2002.

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