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MRS4738

Chemical Structure : MRS4738

CAS No.: 2801625-42-1

MRS4738 (MRS-4738)

Catalog No.: PC-20960Not For Human Use, Lab Use Only.

MRS4738 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 3.11 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MRS4738 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 3.11 nM.

Physicochemical Properties

M.Wt 487.52
Formula C30H24F3NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(O)C1=CC(C2=CC=C([C@@H]3[C@@]4([H])CN[C@@](C4)([H])C3)C=C2)=C5C=CC(C6=CC=C(C(F)(F)F)C=C6)=CC5=C1

References

1. Zhiwei Wen, et al. J Med Chem. 2022 Feb 24;65(4):3434-3459.

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